The continuous neglect of the African male in all reproductive health related programs has contributed to both absence of data that can be used for policy implementation and the refusal of these men to take responsibilities in infertile unions. These prompted the review of the pertinent literature on the state of the art of male infertility in Africa. Past and more recent studies show that the male factor may contribute to infertility among 40 to 60% of infertile couples. Reproductive tract infections (RTIs) have been principally implicated as causes of this social stigma among African males. Other causes included hormonal deficiency and tropical parasitic diseases. Infertility diagnostic problems among African males, range from lack of trained manpower, instrumentation, to patients inability to pay for cost of diagnosis, while management/treatment problems centred around lack of co-ordination among clinicians, negative socio-cultural values to donor agencies’ refusal to fund research in infertility. In particular, the paper recommends the need for an inter-African countries survey on prevalence and determinants of male infertility. It also urges donor agencies to increase funding of infertility related research in Africa.