In South Africa traditional healers use the following plants as immunomodulators: Catharanthus roseus, Centella asiatica, Cnicus benedictus, Dicoma capensis, Hypoxis hemerocallidea, Sutherlandia frutescens and Tulbaghia violacea . The efficacy of these and other plants are being tested at the MRC laboratories for validation. Researchers in China found that a combination of 12 herbs, sold under the trade name Revivo, completely stopped replication of the HIV. Clinical trilas indicated large increase in T4 cells after 4 to 6 months of treatment. Another plant that showed promise was Momordica charantia (bitter gourd) which is found in the tropics like China , India and Africa . It yielded several proteins, dubbed the alpha and beta momorcharins and MPA 30 ( Momordica anti-viral protein of 30 kDaltons), that have anti-HIV activity. Other promising plants from China are: Trichosanthus kirilowii (TAP 29), Phytolaca americana PAP-S) and Excoecaria agalloch (trepenoides). Studies from Japan showed that glycyrrhizin, from Glycyrrhiza glabra and G. uralensis (licorice), appears to maintain immune function and supress HIV replication. Amerindains have been using Echinacea purpurea, E. angustifolia and E. pallida for immune enhancing. Results of a recent double-blind trial showed that one gram three times a day of E. angustifolia extract dramatically boosts the immune function. In the US Viscum album (European mistletoe) extract treatment showed strong immune enhancement in HIV patients, including a 20% increase in CD4+ lymphocytes levels. RevitonilR tablets from Echinacea purpurea and Glycyrrhiza glabra are claimed to raise phagocytosis by 44-53%. 5000 year old Indian Ayurvedic system boasts of many herbal preparations as immnomodulators, viz. Chyawanprash made from 40 herbs in the fruit base of Emblica officinalis and Triphala made from Terminalia balerica, T. chebula and Emblica officinalis . Another combination of plants used in India is Withenia somnifera, Allium sativum and Azadirecta indica.