Different cultures see diseases from different perspectives. The way a culture perceives a disease influences its members’ understanding of the illness as well as the preventive, management and curative measures that are employed. The aim of this study is to reach a better understanding of the management and curative measures employed by an Akan family (Ghana) whose daughter suffered from epilepsy. The community’s perception of the disease was sought in other to unearth how the society’s views influenced the curative methods employed by the patient’s family. The study is done within the frameworks of social construction (Gergen, 1985; Hoffman, 1990) and confessionalism (Van Maanen, 1978). In-depth interviews were carried out between 1991-2001 with twenty five members of the patient’s family, her small community of about one hundred people, and the seven teachers who taught at the school she attended. The life stories about the girl starting from her birth through her school years including discrimination and stigmatization that her family went through are detailed in this study. The study discovered that the overall context in which the family and the community view and manage diseases are of considerable import in aiding medical practitioners to understand how cultures perceive and manage diseases. Such an understanding helps to resolve the controversies that emanate from medical practitioners' ignorance of or misunderstanding about the cultural basis of disease and consequently minimizes the tensions that arise between patients' families and medical practitioners. It is recommended that culture must become an integral part of any form of medical practice.